Author Archives: Jesse
We are hiring computational and experimental scientists to join our team in the Lander Lab at the Broad Institute. Motivated individuals of all levels are encouraged to apply! See the Broad Career Center or contact me for more details.
Congratulations to the team in the Lander and Guttman labs for three of our major papers (all published in the last few weeks): (1) Systematic mapping of functional enhancer-promoter connections with CRISPR interference (Science) This paper was a phenomenal collaboration … Continue reading
Our bioRxiv pre-print for a new story is available here. This story emerged from our efforts to understand whether there are general principles that might explain the functions of many lncRNAs. Through genetic dissection of 12 genomic loci that produce … Continue reading
Our paper about Xist was published in Science today. Read more about the technology we developed here, and also watch my talk on this subject below. In a Perspective in Science, Peter Fraser wrote a very nice summary to our work. However, I thought it might … Continue reading
My talk at the Biology of Genomes meeting at Cold Spring Harbor (May 2013) was recently featured in Science. The talk was titled “Large noncoding RNAs can localize to regulatory DNA targets by exploiting the three-dimensional architecture of the genome”, and featured … Continue reading